Why attending a training course
Continuous professional development.
Up-to-date courses thought by experts in the field.
Unique composition of instructors from all SETAC sectors (business, government and academia).
Well done! Relevant and current content. All speakers strong in experince and all presentations well prepared.
Thank you for the very nice course! Especially useful were the case-studies, to get some “practical” experience.
The course as really great in general, learned a lot! I liked the case study game in the afternoon session.
Very clear and patiently presented, very good pace. Obvious depth of knowledge from presenters.
Congratulations! Very intersting training course! Maybe more information about risk assessment.
Superb course, delivered by real experts in area presenting the latest techniques. “R skills” are necessary.
Sunday, 3 May | 8:15 – 17:00
As recently emphasised by EFSA, toxicokinetic-toxicodynamic (TKTD) models are of particular interest for regulatory risk assessment of pesticides for aquatic organisms. TKTD models can encompass a large set of mechanisms describing the compound kinetics inside organisms as well as their effect at the individual level. Compared to classical dose-response models, TKTD approaches have many advantages: Accounting for temporal aspects of exposure and toxicity, considering data points all along the experiments and not only at the end, and making predictions for untested situations such as realistic field exposure scenarios (e.g., time-variable pulsed exposure profiles).
The General Unified Threshold model of Survival (GUTS) is within the most recent and innovative TKTD framework to deal with survival toxicity test data but is still underused in practice due to specialist programming and statistical skills that are necessary to run models in practice.
This training course aims at presenting the theory of GUTS models and at introducing the participants with dedicated tools allowing the practical use of GUTS models. The course material will be a mixture of lectures and hands-on case studies with ecotoxicological data from recent publications. The course is intended for PhD students, researchers, regulators or any scientist in ecotoxicology and environmental sciences.View the course outline and learning objectives
Instructors: Peter Fantke (Technical University of Denmark), Olivier Jolliett (University of Michigan), Thomas McKone (University of California, Berkeley) and Ralph Rosenbaum (Institute of Agrifood Research and Technology)
There is an increasing need for methods to assess impacts of toxic chemical emissions on human health and ecosystems including consumer exposure. This course provides a practical overview of multimedia chemical fate modelling, near-field and far-field multi-pathway human exposure modelling, ecosystem and human health effects dose-response modelling, and comparative indicators for human-toxicological and ecotoxicological impacts. We explain basic concepts of environmental mass balance modelling including partitioning, first order cross-media transport, and persistence. We further introduce the concept of assessing multiple transfers between near-field and far-field environments and resulting exposures for consumers and the general population, discussing data and models available for detergents, building materials, food contact materials and personal care products. Along a series of practical examples, we will illustrate how fate, exposure, effect and damage factors can be combined to construct factors to characterise chemical emissions and chemicals in consumer products, building on the USEtox scientific consensus model and USEtox-compatible near-field models. We will conclude with a demonstration of how the models can be used in various applications, including the prioritisation and ranking of chemicals for institutions like the European Commission or the U.S. Environmental Protection Agency.View the course outline and learning objectives